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Old 01-25-2021, 01:19 PM   #121
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TWiV 710: COVID-19 clinical update #46 with Dr. Daniel Griffin

TWiV 710 contains COVID-19 clinical update #46, Daniel Griffin discusses the BinaxNow rapid antigen test, efficacy of Bamlanivimab in nursing homes, associations of serum vitamin D concentrations with in-hospital mortality and need for invasive mechanical ventilation, trials of IL-6 receptor antagonists, effects of anticoagulants on in-hospital mortality, and symptom persistence in outpatients.

Links for this episode
  • Evaluation of Abbott BinaxNOW (MMWR) 17:00
  • Lilly mAb in nursing homes (WSJ) 18:16
  • Vitamin D and COVID-19 severity (Mayo Clin Proc) 19:56
  • Anticoagulation, aspirin, in-hospital mortality in COVID-19 (medRxiv) 21:19
  • Long COVID symptoms in outpatients (Ann Int Med) 27:07
  • {url=https://www.microbe.tv/twiv/twiv-710-letters/]Letters read[/url] on TWiV 710 27:48
  • Timestamps by Jolene. Thanks!
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Old 01-25-2021, 01:22 PM   #122
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TWiV 711: The New Heal

In Episode 711, the TWiVers review Bidenís national strategy for COVID-19 responses and pandemic preparedness, and an evaluation of the BinaxNOW rapid antigen test for SARS-CoV-2 infection.

Links for this episode
  • Bidenís COVID-19 strategy (pdf) 10:30
  • CDC evaluation of BinaxNOW antigen test (MMWR) 52:09
  • FDA instructions for BinaxNOW test (pdf) 52:28
  • Adam Neely on Sea Shanties (YouTube) 1:05:29
  • Letters read on TWiV 711 1:06:55
  • Timestamps by Jolene. Thanks!
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Old 02-03-2021, 12:55 PM   #123
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TWiV 712: Deutscher Virus Wahnsinn

In Episode 712, Gisa, Steffi, and Cťsar join TWiV to discuss their careers, their research, and the COVID-19 pandemic in Germany.

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Old 02-03-2021, 12:59 PM   #124
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TWiV 713: COVID-19 clinical update #47 with Dr. Daniel Griffin

In COVID-19 clinical update #47 (TWiV 713), Daniel Griffin reviews phase 3 results for Novavax and J&J vaccines, transmission in K-12 settings in Wisconsin, data on Lilly and Regeneron monoclonal antibody therapy, and a study of colchicine for treatment of disease.

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Old 02-03-2021, 01:02 PM   #125
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TWiV 714: The shape of spike with Jason McLellan

In Episode 714, Jason McLellan joins TWiV to reveal all we know about the SARS-CoV-2 spike protein, followed by Novavax and J&S phase 3 results and a discussion of variants of concern: neutralization by vaccine-induced antibodies, transmission, and virulence.

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'Everything takes longer than you think; nothing is as simple as it seems; if anything can go wrong it will'
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Old 02-10-2021, 09:25 AM   #126
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TWiV 715: Fauci ouchy

In Episode 715, TWiV explains why hydroxychloroquine failed in humans despite showing antiviral effects in cells, and reviews the published data on the Pfizer/BioNTech mRNA vaccine.

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Old 02-10-2021, 09:29 AM   #127
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TWiV 716: COVID-19 clinical update #48 with Dr. Daniel Griffin

In TWiV's COVID-19 clinical update #48, Daniel Griffin reviews effect of spike amino acid changes on neutralization with monoclonal antibodies, Sputnik V safety and efficacy results, increased reactogenicity after a single vaccine dose in seropositive individuals, single dose vaccination in seropositive health care workers, and results of three clinical trials on the use of anticoagulants.

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'Everything takes longer than you think; nothing is as simple as it seems; if anything can go wrong it will'
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Old 02-10-2021, 09:32 AM   #128
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TWiV 717: Paul and Theodora, pandemic explorers

In TWiV 717, Theodora and Paul return to TWiV to explain how they quickly pivoted their retrovirus laboratories towards SARS-CoV-2, their work on the antibody response to infection and its durability, and the emergence of variants with increased resistance to neutralization.

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Old 02-17-2021, 09:43 AM   #129
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TWiV 718: Recombining vaccine schedules

In Episode 218, TWiV explores single dose administration and timing of second dose of AZD1222 COVID-19 vaccine, safety and efficacy of Sputnik V, and control of coronavirus recombination by a viral proofreading exonuclease.

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Old 02-17-2021, 09:47 AM   #130
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TWiV 719: COVID-19 clinical update #49 with Dr. Daniel Griffin

In COVID-19 clinical update #49, Daniel Griffin discusses CDC guidelines on mask use, drop in test frequency in the US, resurgence of COVID-19 in Brazil, possible impact of Pfizer vaccine on viral load, EUA for bamlanivimab and etesevimab administered together, and preliminary results of Tocilizumab in hospitalized patients.

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'Everything takes longer than you think; nothing is as simple as it seems; if anything can go wrong it will'
O'Grady's Law
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Old 02-17-2021, 09:51 AM   #131
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TWiV 720: With vaccines, Offit is on it

In Episode 720, Paul Offit joins TWiV to discuss all things vaccine, including how COVID-19 vaccine development was accelerated, whether the vaccines are safe and efficacious, the difference between an EUA and a licensed vaccine, sterilizing immunity, herd immunity, and much more.

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'Everything takes longer than you think; nothing is as simple as it seems; if anything can go wrong it will'
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Old 02-25-2021, 11:37 AM   #132
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TWiV 721: COVID-19 clinical update #50 with Dr. Daniel Griffin

In COVID-19 clinical update #50, Daniel Griffin discusses CDC guidance on school opening, decreased viral load after vaccination, randomized clinical trial of vitamin D treatment, a study of zinc plus vitamin C, anticoagulation therapy effect on mortality, and multi system inflammatory phase in children.

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Old 02-25-2021, 11:40 AM   #133
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TWiV 722: More coronaviruses in the pipeline

In TWiV 722 the entire team assembles to discuss resurgence of COVID-19 in Manaus, Brazil, discovery of SARS-CoV-2 related viruses in bats in Southeast Asia, and increased Ct values after administration of mRNA vaccine.

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Old 02-25-2021, 11:45 AM   #134
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TWiV 723: COVID-19 palliative care with Ginger Campbell, MD

In Episode 723, Ginger Campbell joins TWiV to discuss palliative care for COVID-19 patients, and how to approach the disease from a goals of care perspective.

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